High Efficiency Rapid Mixer Granulator GHL150 80 Output Capacity Kg / Batch
High efficiency rapid shear mix granulator working principle
Wet granulation is often used in solid preparations for medicines that require the addition of a binder (such as alcohol, dextrin, etc.) for granulation. It is also suitable for 1 tablet when adding adhesive to enhance the compressibility and adhesion of the powder; 2 when the capsule filling or tableting requires fluidity, usually liquid and high dose materials can be used; 3 pairs of low The dosage of the drug is evenly distributed and the color is good, and can also be solved by this method; 4 the solid preparation can also be used in this method to increase the dissolution rate of the drug by using a suitable solvent and a binder.
In addition, the horizontal high-speed mixing granulator has a working time of less than 10 minutes per batch, and can produce 80 to 200 kg, which is 4-5 times higher than the traditional process. Secondly, the binder is reduced by 25% compared to the conventional process, and the drying time is shortened. The granules are approximately spherical and have good fluidity. At the same time, the outlet can be connected to the boiling and drying, and the powder can be added to the wet granulator by a hoist or a vacuum feeder.
Comparison of common methods of wet granulation and horizontal high-efficiency wet granulation
There are two types of wet granulation equipment: horizontal and vertical. Generally speaking, the horizontal wet granulator is superior to the vertical one. The following can be seen by comparing horizontal and vertical wet
|output capacity kg/batch||15||50||80||100||130||200||280|
|admix speed r.p.m||200/400||180/270||180/270||180/270||140/220||106/155||80/120|
|admix power kw||4/5.5||6.5/8||9/11||9/11||13/16||18.5/22||22/30|
|cutting speed r.p.m||1500/3000||1500/3000||1500/3000||1500/3000||1500/3000||1500/3000||1500/3000|
|cutting power kw||1.3/1.8||2.4/3||4.5/5.5||4.5/5.5||4.5/5.5||6.5/8||9/11|
|compressed air consumption m3/min||0.6||0.9||0.9||0.9||1.1||1.5||1.8|